A new study by researchers in Spain found that a "triple therapy" eliminates pancreatic tumors in mice.
Pancreatic cancer is one of the most aggressive tumors with the worst prognosis, partly due to the rapid emergence of resistance to treatment.
But a new study from the Spanish National Cancer Research Center (CNIO) reveals that it is possible to eliminate pancreatic tumors in mice and prevent them from returning using triple combination therapy.
"These studies pave the way for designing novel combination therapies that could improve survival of patients with pancreatic ductal adenocarcinoma," the authors said in a statement.
"These results set the direction for the development of new clinical trials," she added, writing Euronews, the Telegraph reports.
According to an article on another portal, the researchers designed a strategy that targets three key aspects of this cancer: the mutation that initiates the tumor (called KRAS) and the two proteins involved that promote the spread, survival, and growth of this cancer (called EGFR and STAT3).
Meanwhile, the Euronews article highlights that in Spain, more than 10,300 cases of this type of cancer are diagnosed each year, with a five-year survival rate of less than 10 percent.
However, although the result could be a milestone in the fight against cancer, the study authors issued a warning.
"We are not yet in a position to conduct clinical trials with triple therapy. The authors themselves warn that optimizing this combination for patients will be a complex process, although they are confident that the finding will set the course for future trials," they said. /Telegrafi/
